Diaphonised mouse foetus in resin block (alcian blue)
Department of Histology, University of Melbourne
Mouse foetus diaphonised and preserved in a resin block. The foetus has been stained with alcian blue dye to highlight the cartilage. Diaphonisation is a biological staining process first developed by scientists G. Dingerkus and L.D. Uhler in 1977. The specimen – usually a small vertebrate – is made transparent by soaking in trypsin, a digestive enzyme, and then stained with specialised dyes that adhere to specific types of tissues, such as bone, muscle or cartilage.
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